Drug trial offers hope for kids with painful, disfiguring vascular growths

NCT ID NCT00975819

First seen Jan 06, 2026 · Last updated Apr 17, 2026 · Updated 17 times

Summary

This study tested whether the drug sirolimus is safe and effective for treating complicated vascular anomalies in children and young adults up to age 31. These are serious, often painful growths or malformations of blood or lymph vessels that can cause disfigurement and organ problems. Researchers gave sirolimus to 61 participants and measured its effects on shrinking the growths, improving daily function, and enhancing quality of life.

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Contacts and locations

Locations

  • Children's Hospital Boston

    Boston, Massachusetts, 02115, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

Conditions

Explore the condition pages connected to this study.