New patch could tame earlobe keloid scars after surgery

NCT ID NCT07596628

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial tests whether small interfering RNA (siRNA) microneedle patches can improve the appearance of earlobe keloid scars after laser surgery. About 158 adults with earlobe keloids will receive either standard steroid injections alone or steroid injections plus the siRNA patches. The study will compare scar appearance and symptoms over several months to see if the patches offer added benefit.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Small interfering RNA (siRNA) microneedle patches

What this could lead to

If successful, this could offer a new way to reduce keloid scarring after earlobe surgery, potentially improving scar appearance and symptoms.

What could go wrong

This is an early Phase 2 trial with a small sample size, so results may not be conclusive. The patches are experimental and may not work better than standard treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

keloid severe cutaneous adverse reaction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Skin Centre

    Singapore, 308205, Singapore

    Contact

    Contact

    Contact Phone: •••-•••-••••

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