New patch could tame earlobe keloid scars after surgery
NCT ID NCT07596628
First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times
Summary
This Phase 2 trial tests whether small interfering RNA (siRNA) microneedle patches can improve the appearance of earlobe keloid scars after laser surgery. About 158 adults with earlobe keloids will receive either standard steroid injections alone or steroid injections plus the siRNA patches. The study will compare scar appearance and symptoms over several months to see if the patches offer added benefit.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Small interfering RNA (siRNA) microneedle patches
- What this could lead to
- If successful, this could offer a new way to reduce keloid scarring after earlobe surgery, potentially improving scar appearance and symptoms.
- What could go wrong
- This is an early Phase 2 trial with a small sample size, so results may not be conclusive. The patches are experimental and may not work better than standard treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Skin Centre
Singapore, 308205, Singapore