First human test of experimental COVID-19 inflammation drug

NCT ID NCT04622332

Summary

This completed early-stage study tested whether an experimental drug called SIR1-365 is safe for hospitalized patients with severe COVID-19. Researchers enrolled 45 adults to receive either the drug or a placebo for 14 days, monitoring side effects and whether it helped reduce inflammation or improve breathing. The main goal was to check safety, while also looking at whether patients needed less oxygen support.

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Contacts and locations

Locations

  • Aga Khan University Hospital

    Karachi, Sindh, 74800, Pakistan

  • Baptist Medical Center

    Jackson, Mississippi, 39202, United States

  • Dow University Hospital, Ojha Karachi

    Karachi, Sindh, 74200, Pakistan

  • Hospital Civil Fray Antonio Alcalde

    Guadalajara, Jalisco, 14050, Mexico

  • Hospital Universitario "Dr. José Eleuterio González"

    Monterrey, Nuevo León, 64460, Mexico

  • Media Sur - Medica Sur Tlalpan

    Tlalpan, Mexico City, 14050, Mexico

  • OSF St. Francis Medical Center

    Peoria, Illinois, 61637, United States

  • Sindh Infectious Disease Hospital

    Karachi, Sindh, 74200, Pakistan

  • Triple O Research Institute

    West Palm Beach, Florida, 33407, United States

Conditions

Explore the condition pages connected to this study.