New drug could help lung transplant patients fight rejection

NCT ID NCT06948097

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 33 times

Summary

This early-stage study tests a drug called fostamatinib in 30 adults who have received a lung transplant and developed donor-specific antibodies, which increase the risk of organ rejection. Participants take the drug or a placebo daily for 8 weeks while continuing standard care. The main goal is to see if the drug is safe and tolerable, with a focus on preventing antibody-mediated rejection.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Inova Health System Foundation

    Falls Church, Virginia, 22042, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Johns Hopkins University School of Medicine

    Baltimore, Maryland, 21224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Heart, Lung and Blood Institute (NHLBI)

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford University School of Medicine

    Stanford, California, 94305, United States

  • University of Utah Health

    Salt Lake City, Utah, 84132, United States

Conditions

Explore the condition pages connected to this study.