Could a simple Anti-Gas drug make colonoscopies more effective?
NCT ID NCT07674160
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study investigates whether adding simethicone, an anti-foaming agent, to standard bowel preparation improves colon cleanliness during water-exchange colonoscopy. About 180 adults undergoing screening or diagnostic colonoscopy will be randomly assigned to receive either simethicone plus polyethylene glycol (PEG) or PEG alone. The goal is to see if simethicone reduces bubbles and improves visibility, potentially leading to better detection of polyps and adenomas.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
simethicone
What this could lead to
If effective, adding simethicone could offer a simple, low-cost way to improve colonoscopy quality and polyp detection.
What could go wrong
This is a small, single-center study. The benefit may be modest or not apply to other colonoscopy techniques.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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