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Could a gas-busting ingredient in colonoscopy prep help spot more cancers?

NCT ID NCT07696793

Recruiting now Diagnosis Sponsor: Fundacion Clinic per a la Recerca Biomédica Source: ClinicalTrials.gov ↗

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This trial compares two bowel-cleansing solutions used before screening colonoscopy for colorectal cancer. One contains simethicone, an anti-gas agent, while the other does not. The study aims to see if the simethicone-containing solution helps doctors detect more adenomas (precancerous polyps) during the procedure. Participants are adults aged 50–69 who have had a positive fecal occult blood test and are scheduled for a screening colonoscopy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Clensia® (simethicone-containing bowel-cleansing solution)
What this could lead to
If it works, this could improve the detection of polyps and early-stage colorectal cancer during screening colonoscopies, potentially saving more lives through earlier diagnosis.
What could go wrong
This is a Phase 4 trial comparing two existing products, so the difference may be small. The main risk is discomfort from the bowel preparation itself, such as bloating or nausea.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL CANCER EARLY DETECTION

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital Clínic de Barcelona

    RECRUITING

    Barcelona, Barcelona, 08036, Spain

    Contact Email: •••••@•••••

    Contact

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