New hope for advanced tumors? first human trial of SIM0505 begins
NCT ID NCT06792552
First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 26 times
Summary
This early-stage study tests a new drug, SIM0505, in adults with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety, find the right dose, and see if the drug can shrink tumors. About 414 people will take part across multiple centers.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Affiliated Hospital of Jining Medical University
RECRUITINGJining, Shandong, 272000, China
Contact Phone: •••-•••-••••
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Cancer Hospital of Shandong First Medical University
RECRUITINGJinan, Shandong, 250117, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Emory Winship Cancer Institute
RECRUITINGAtlanta, Georgia, 30322, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fudan University Shanghai Cancer Center
RECRUITINGShanghai, Shanghai Municipality, 200032, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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HunanCancer Hospital
RECRUITINGChangsha, Hunan, 430100, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10128, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Liaoning Cancer Hospital & Institute
NOT_YET_RECRUITINGShenyang, China, 110092, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Roswell Park Cancer Institute
RECRUITINGBuffalo, New York, 14263, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sarah Cannon Research Institute (SCRI) - Lake Nona
RECRUITINGOrlando, Florida, 32827, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sarah Cannon Research Institute (SCRI) - Nashville
RECRUITINGNashville, Tennessee, 37203, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sun Yat-sen University Cancer Center
RECRUITINGGuangzhou, Guangdong, 510060, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Fourth Hospital of Hebei Medical University (Heibei Tumor Hospital)
NOT_YET_RECRUITINGShijiazhuang, China, 050010, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The first medical center of PLA general hospital
RECRUITINGBeijing, Beijing Municipality, 100000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UT Health San Antonio - Mays Cancer Center
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University Medical Center of New Orleans LSU-LCMC Health Cancer Center
NOT_YET_RECRUITINGNew Orleans, Louisiana, 70112, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
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