New gel could stop tooth decay in kids without drilling

NCT ID NCT06241261

First seen Mar 18, 2026 · Last updated Jun 23, 2026 · Updated 16 times

Summary

This study tests whether a gel made with silver diamine fluoride can stop cavities in preschool children as well as the liquid version. About 630 healthy kids with at least one cavity will get the gel or solution every six months for 30 months. Researchers will check if the cavities harden and stop growing.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • The University of Hong Kong

    Hong Kong, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

silver diamine fluoride gel

What this could lead to

If it works, this could offer a simpler, less messy way to stop cavities in young children without drilling.

What could go wrong

This is a mid-stage trial with 630 children, so results are not final. The gel may not work as well as the solution, or children may find it hard to tolerate.

Conditions

The condition(s) this trial relates to.

cardiac arrest dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.