Silver-coated chest tube shows promise for cancer fluid relief
NCT ID NCT02649894
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a new type of chest tube coated with silver nitrate against a standard tube for people with recurrent fluid buildup in the chest due to cancer. The goal was to see if the coated tube could seal the space and prevent fluid from coming back more effectively. 119 adults with symptomatic malignant pleural effusion took part. The main measure was how many people achieved pleurodesis (lung sealing) without recurrence.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- silver nitrate-coated indwelling pleural catheter
- What this could lead to
- If it works, this could offer a more effective way to control fluid buildup in the chest for people with cancer, reducing the need for repeat procedures.
- What could go wrong
- This is a small, completed study (119 people) comparing a coated catheter to an approved one. The coating may not provide significant benefit, and there is a risk of infection or other complications from the device.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MALIGNANT PLEURAL EFFUSION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Beth Israel Deconess Medical Center West
Boston, Massachusetts, 02215, United States
-
Duke University
Durham, North Carolina, 27710, United States
-
Great Western Hospital
Swindon, United Kingdom
-
Heart Center Research
Huntsville, Alabama, 35801, United States
-
Huntsman Cancer Institute
Salt Lake City, Utah, 84112, United States
-
Johns Hopkins Hospital
Baltimore, Maryland, 21287, United States
-
Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
-
Moffitt Cancer Center
Tampa, Florida, 33612, United States
-
Northwestern Unversity
Chicago, Illinois, 60611, United States
-
Oxford Center for Respiratory Medicine, Churchill Hospital
Oxford, United Kingdom
-
SUNY Upstate Hospital
Syracuse, New York, 13210, United States
-
Southmead Hospital
Bristol, United Kingdom
-
St. Vincent Medical Group
Indianapolis, Indiana, 46260, United States
-
Stanford University School of Medicine/ Stanford Cancer Institute
Stanford, California, 94305, United States
-
UNC Hospital
Chapel Hill, North Carolina, 27599, United States
-
University of Nebraska Medical Center
Omaha, Nebraska, 68198, United States
-
University of Texas, MD Anderson Cancer Center
Houston, Texas, 77030, United States
-
Vanderbuilt University
Nashville, Tennessee, 37232, United States
-
Washington Universtiy School of Medicine, Barnes Jewish Hospital
St Louis, Missouri, 63110, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Chest-Injected drug drain Cancer's fluid trap?
- Lung fluid may replace biopsies for cancer testing
- Catheter or surgery? new study seeks best way to ease breathing in cancer patients
- Diabetes drug metformin may boost chemo for ovarian cancer
- Scientists use patients' own lung fluid cells to fight advanced cancer
- New combo aims to keep cancer fluid at bay