Viagra cream for women? early trial tests blood flow

NCT ID NCT05765487

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-stage study tested a cream containing sildenafil (the active ingredient in Viagra) on 13 healthy premenopausal women. Researchers used thermography to measure changes in vulvar blood flow while participants watched explicit videos. The goal was to see if the cream increases blood flow compared to a placebo or a cream with only L-arginine.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
sildenafil cream
What this could lead to
If it works, this could point toward a topical treatment for sexual arousal difficulties in women.
What could go wrong
This is a very early Phase 1 study with only 13 healthy women, so results may not apply to those with the condition. The cream may not improve arousal or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Sexual Dysfunctions, Psychological

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Pharma Medica Research, Inc.

    Mississauga, Ontario, Canada

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