Can we predict dangerous spleen attacks in sickle cell babies?
NCT ID NCT01207037
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study followed 58 babies with sickle cell disease from 3 months to 2 years old to find early clues that might predict a life-threatening spleen complication called acute splenic sequestration. Researchers took blood samples and used special scans to measure spleen size and function. The goal was to identify clinical, biological, and genetic markers that could help doctors spot high-risk children sooner.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors predict which children with sickle cell disease are at highest risk for dangerous spleen problems, allowing earlier monitoring or treatment.
- What could go wrong
- This is a small, observational study that only looks for patterns—it does not test a treatment. The findings may not apply to all children or lead to a proven prediction tool.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Necker Hospital
Paris, 75015, France