Can we predict dangerous spleen attacks in sickle cell babies?
NCT ID NCT01207037
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study followed 58 babies with sickle cell disease from 3 months to 2 years old to find early clues that might predict a life-threatening spleen complication called acute splenic sequestration. Researchers took blood samples and used special scans to measure spleen size and function. The goal was to identify clinical, biological, and genetic markers that could help doctors spot high-risk children sooner.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors predict which children with sickle cell disease are at highest risk for dangerous spleen problems, allowing earlier monitoring or treatment.
What could go wrong
This is a small, observational study that only looks for patterns—it does not test a treatment. The findings may not apply to all children or lead to a proven prediction tool.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Necker Hospital
Paris, 75015, France