Gene hunt: could a hidden DNA code explain why sickle cell hits some harder?
NCT ID NCT03685721
Summary
This study aims to understand why some people with sickle cell disease have more severe symptoms than others. Researchers are looking at a specific gene called PKLR to see if different versions of it affect how red blood cells work, which could worsen the disease. They will collect blood samples from 800 adults of African descent, with and without sickle cell, to analyze their genes and cell chemistry. The goal is to gather knowledge that could lead to future treatments, but this study itself does not provide any treatment.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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