Tracking sickle cell patients on new medication for 5 years

NCT ID NCT04930445

Terminated Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

Summary

This study followed 265 people with sickle cell disease who were already taking Oxbryta, a medication approved to help manage the condition. Researchers collected real-world data over up to 5 years to understand how the drug affects patients' blood health, complications, and quality of life during normal use. The goal was to learn about the long-term effectiveness and safety of Oxbryta outside of controlled clinical trials.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Augusta University

Augusta, Georgia, 30912, United States
Augusta University - Clinical Trials Office (clinic)

Augusta, Georgia, 30912, United States
Bass Center for Childhood Cancer and Blood Disorders (Stanford Lucile Packard Children's Hospital)

Palo Alto, California, 94304, United States
Boston University Medical Center

Boston, Massachusetts, 02118, United States
Center for Inherited Blood Disorders

Orange, California, 92868, United States
Children's Blood and Cancer Center at Dell Children's Medical Center

Austin, Texas, 78723, United States
Dell Children's Medical Center

Austin, Texas, 78723, United States
Department of Pediatrics, Hematology section

Palo Alto, California, 94304, United States
Duke University Hospital

Durham, North Carolina, 27710, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
ECU Health Medical Center

Greenville, North Carolina, 27834, United States
ECU Health Medical Center Laboratory

Greenville, North Carolina, 27834, United States
East Carolina University

Greenville, North Carolina, 27834-4300, United States
Foundation for Sickle Cell Disease Research

Hollywood, Florida, 33023, United States
INOVA Health

Falls Church, Virginia, 22042-2325, United States
Inova Schar Cancer Institute

Fairfax, Virginia, 22031, United States
Levine Cancer Institute

Charlotte, North Carolina, 28204, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Medical University of South Carolina Shawn Jenkins Women's and Children's Hospital

Charleston, South Carolina, 29425, United States
Mississippi Center for Advanced Medicine

Madison, Mississippi, 39110, United States
Montefiore Medical Center

The Bronx, New York, 10467, United States
Nemours Alfred I duPont Hospital for Children

Wilmington, Delaware, 19803, United States
Nemours Children's Health, Wilmington

Wilmington, Delaware, 19803, United States
Nemours Children's Specialty Care

Jacksonville, Florida, 32207, United States
Newark Beth Israel Medical Center

Newark, New Jersey, 07112, United States
Phoenix Children's Hospital

Phoenix, Arizona, 85016, United States
St. Jude Children's Research Hospital

Memphis, Tennessee, 38105, United States
Stanford Children's Hospital

Palo Alto, California, 94304, United States
UPMC Montefiore Hospital

Pittsburgh, Pennsylvania, 14213, United States
UPMC Presbyterian

Pittsburgh, Pennsylvania, 15213, United States
UPMC Sickle Cell Center

Pittsburgh, Pennsylvania, 15123, United States
University of California, San Diego

La Jolla, California, 92093-0987, United States
University of Connecticut Health

Farmington, Connecticut, 06030-1163, United States
University of Connecticut Health

Farmington, Connecticut, 06030, United States
University of Illinois Hospital and Health Sciences System

Chicago, Illinois, 60612, United States
University of Illinois Hospital and Health Sciences System(UI Health)

Chicago, Illinois, 60612, United States
University of Illinois at Chicago (UIC) Clinical Research Center

Chicago, Illinois, 60612, United States
University of Illinois at Chicago (UIC) Sickle Cell Center

Chicago, Illinois, 60612, United States
University of Maryland Medical Center

College Park, Maryland, 21201, United States
University of Miami Hospital

Miami, Florida, 33136, United States
University of Pittsburgh Medical Center (UPMC)

Pittsburgh, Pennsylvania, 15261, United States
University of South Alabama

Mobile, Alabama, 36617, United States
University of Texas Health Science Center at Houston

Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.

SICKLE CELL DISEASE