New Two-Pronged cancer drug enters first human tests

NCT ID NCT04606472

Summary

This is an early-stage safety study testing a new experimental drug called SI-B003 in patients with advanced solid tumors that have stopped responding to standard treatments. The drug is designed to block two different pathways (PD-1 and CTLA-4) that cancer cells use to hide from the immune system. The main goals are to find a safe dose and see how the body processes the drug in about 60 participants.

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Contacts and locations

Locations

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, 100142, China

  • Chongqing University Cancer Hospital

    Chongqing, Chongqing Municipality, China

  • Henan Cancer Hospital

    Zhengzhou, Henan, 450008, China

  • Hubei Cancer Hospital

    Wuhan, Hubei, China

  • Shanghai Central Hospital

    Shanghai, Shanghai Municipality, China

  • The First Affiliated Hospital of Xiamen University

    Xiamen, Fujian, China

  • Union Hospital Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, China

  • West China Hospital, Sichuan University

    Chengdu, Sichuan, China

Conditions

Explore the condition pages connected to this study.