New antibody drug shows promise in early cancer trial

NCT ID NCT04603287

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 27 times

Summary

This early-stage study tests a new drug called SI-B001 in about 60 people with advanced solid tumors that have not responded to standard treatments. The drug is a bispecific antibody designed to target two cancer-related proteins, EGFR and HER3. The main goals are to check safety, find the right dose, and see if the drug can shrink tumors. This is not a cure, but aims to control the disease.

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Contacts and locations

Locations

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510006, China

  • West China Hospital,Sichuan University

    Chengdu, Sichuan, China

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, China

Conditions

Explore the condition pages connected to this study.