Experimental drug SHR-A2009 takes first steps against Hard-to-Treat cancers
NCT ID NCT05114759
First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This early-phase trial is testing an experimental drug called SHR-A2009 in people with advanced solid tumors that have stopped responding to standard treatments or have no standard options. The main goals are to find a safe dose and to understand the drug's side effects and how the body processes it. The study will also look for early signs that the drug might shrink tumors.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- an experimental drug called SHR-A2009
- What this could lead to
- If successful, this could lead to a new treatment option for people with advanced solid tumors who have few alternatives.
- What could go wrong
- This is a very early Phase 1 trial focused on safety and dosing, so it is unknown if SHR-A2009 will effectively shrink tumors or improve survival. Side effects are also not yet fully understood.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ADVANCED SOLID TUMOR are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Asan Medical Center
Seoul, Seoul, 05505, South Korea
-
Chongqing Cancer Hospital
Chongqicun, Chongqi, 400000, China
-
First Affiliated Hospital of Kunming Medical University
Kunming, Yunnan, 650000, China
-
Fujian Provincial Cancer Hospital
Fuzhou, Fujian, 350000, China
-
Guangdong Provincial People's Hospital
Guangzhou, Guangdong, 510080, China
-
Hunan Cancer Hospital
Changsha, Hunan, 410000, China
-
National Cancer Center Hospital
Tokyo, Tokyo, 104-0045, Japan
-
National Cancer Center Hospital East
Chiba, Chiba, 277-8577, Japan
-
Samsung Medical Center
Seoul, Seoul, 06351, South Korea
-
Seoul National University Hospital
Seoul, Seoul, 03080, South Korea
-
Shandong Cancer Hospital&Institute
Jinan, Shandong, 250000, China
-
Sichuan Cancer Hospital & Institute
Chengdu, Sichuan, 610000, China
-
The First Hospital of JiLin University
Changchun, Jlin, 132000, China
-
The Second Affiliated Hospital of Air Force Military University Tangdu Hospital
Xi’an, Shanxi, 710000, China
-
The Second Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, 330000, China
-
West China Hospital,Sichuan University
Chengdu, Sichuan, 610000, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could an AI-Designed pill take on Hard-to-Treat cancers?
- Can a new nucleotide analogue boost cancer treatment?
- Can a new Liposome-Wrapped drug shrink Hard-to-Treat solid tumors?
- Can a new antibody help the immune system fight advanced cancers?
- Can an experimental pill slow advanced solid tumors? a phase 1 trial puts HW221043 to the test.
- Can a cancer vaccine train the body to fight advanced tumors?