New drug shows promise for rare cholesterol disease

NCT ID NCT06723652

First seen Oct 31, 2025 · Last updated May 10, 2026 · Updated 19 times

Summary

This study tested a new medicine called SHR-1918 in 55 people with homozygous familial hypercholesterolemia (HoFH), a rare genetic condition causing very high cholesterol. The goal was to see if the drug could safely lower bad cholesterol levels. Participants received either the drug or a placebo, and their cholesterol was measured over 12 to 24 weeks.

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Contacts and locations

Locations

  • The Second Xiangya Hospital of Central South University Hospital

    Changsha, Hunan, 410000, China

Conditions

Explore the condition pages connected to this study.