New hope for fighting genetic cholesterol disorder

This study tested whether a new drug called SHR-1918 could lower bad cholesterol in people with a rare, severe genetic condition called homozygous familial hypercholesterolemia. Fifty-five participants received either the drug or a placebo for 24 weeks while continuing their usual cholesterol medications. Researchers measured how much the drug reduced LDL cholesterol levels over 12 and 24 weeks to see if it could help control this difficult-to-treat condition.