Could a 17-Week TB regimen replace 6 months of treatment?

NCT ID NCT05766267

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 26 times

Summary

This study tests whether two shorter, 17-week drug combinations can treat pulmonary tuberculosis as effectively as the standard 6-month regimen. About 288 adults and teens with active TB will take one of three daily pill regimens. The goal is to see if the shorter treatments clear the infection faster and are safe, potentially making it easier for patients to complete therapy.

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Contacts and locations

Locations

  • McGill University Health Centre

    Montreal, Canada

  • TBTC Site 09 University of Cape Town Lung Institute (Pty) Ltd

    Mowbray, Cape Town, 7700, South Africa

  • TBTC Site 26 Seattle & King County TB Control Program

    Seattle, Washington, 98104, United States

  • TBTC Site 30 Uganda-Case Western Reserve Research Collaboration

    Kampala, Uganda

  • TBTC Site 45 Les Centres Gheskio (INLR)

    Port-au-Prince, Ouest, HT6110, Haiti

  • TBTC Site 67 GHESKIO centers IMIS

    Port-au-Prince, Ouest, HT 6124, Haiti

  • TBTC Site 76 CAB-V. Can Tho Province, Vietnam - Thot Not District TB Unit

    Can Tho, Can Tho City, 70000, Vietnam

  • Vancouver, British Columbia Centre for Disease Control

    Vancouver, Canada

Conditions

Explore the condition pages connected to this study.