TB prevention breakthrough? 6-Week regimen could replace months of treatment
NCT ID NCT03474029
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a new 6-week daily rifapentine regimen to the standard 12-16 week rifamycin-based treatment for latent tuberculosis infection (LTBI). The goal is to see if the shorter treatment is just as safe and effective at preventing active TB. About 3,400 people at higher risk for TB will participate and be followed for 2 years.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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British Columbia Centre for Disease Control
RECRUITINGVancouver, British Columbia, Canada
Contact
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Calgary TB Clinic
RECRUITINGCalgary, Alberta, T1Y 6H6, Canada
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Denver Health and Hospital Authority
RECRUITINGDenver, Colorado, 80204, United States
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Desmond Tutu TB Center
NOT_YET_RECRUITINGStellenbosch, South Africa
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Edmonton TB Clinic
RECRUITINGEdmonton, Alberta, Canada
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George Washington University
RECRUITINGWashington D.C., District of Columbia, 20001, United States
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Ho Chin Minh City-District 6 TB Unit
RECRUITINGHo Chi Minh City, Vietnam
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Ho Chin Minh City-Phoi Viet Resportory Centre
RECRUITINGHo Chi Minh City, Vietnam
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Joint Clinical Research Centre/ Makerere Univ Med Sch
RECRUITINGKampala, Uganda
Contact
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Les Centres Gheskio (INLR) CRS
RECRUITINGPort-au-Prince, Haiti
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Liverpool Hospital
RECRUITINGSydney, Australia
Contact
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McGill University Health Centre
RECRUITINGMontreal, Quebec, H3A 0G4, Canada
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National Referral University Hospital for Pneumo-physiology
ACTIVE_NOT_RECRUITINGCotonou, Benin
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New York City Bureau of TB Control
RECRUITINGNew York, New York, 11201, United States
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New York Harbor Healthcare System
RECRUITINGManhattan, New York, 10001, United States
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Paramatta Chest
RECRUITINGSydney, Australia
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Royal Prince Alfred Hospital
RECRUITINGSydney, Australia
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San Antonio VA
ACTIVE_NOT_RECRUITINGSan Antonio, Texas, 78201, United States
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Seattle King County Health Department
RECRUITINGSeattle, Washington, 98101, United States
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Toronto Western Hospital
RECRUITINGToronto, Ontario, M5P 1N5, Canada
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Washington DC VA Medical Center
RECRUITINGWashington D.C., District of Columbia, 20001, United States
Contact