Shorter TB prevention: 6-Week daily pill could replace months of treatment
NCT ID NCT03474029
First seen May 07, 2026 · Last updated May 07, 2026
Summary
This study compares a new 6-week daily rifapentine regimen to standard 12-16 week treatments for latent tuberculosis infection (LTBI) in people at high risk of developing active TB. About 3,400 participants will be randomly assigned to either the short or longer treatment and followed for 24 months. The goal is to see if the shorter option is as safe and effective at preventing active TB disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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British Columbia Centre for Disease Control
RECRUITINGVancouver, British Columbia, Canada
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Calgary TB Clinic
RECRUITINGCalgary, Alberta, T1Y 6H6, Canada
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Denver Health and Hospital Authority
RECRUITINGDenver, Colorado, 80204, United States
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Desmond Tutu TB Center
NOT_YET_RECRUITINGStellenbosch, South Africa
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Edmonton TB Clinic
RECRUITINGEdmonton, Alberta, Canada
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George Washington University
RECRUITINGWashington D.C., District of Columbia, 20001, United States
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Ho Chin Minh City-District 6 TB Unit
RECRUITINGHo Chi Minh City, Vietnam
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Ho Chin Minh City-Phoi Viet Resportory Centre
RECRUITINGHo Chi Minh City, Vietnam
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Joint Clinical Research Centre/ Makerere Univ Med Sch
RECRUITINGKampala, Uganda
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Les Centres Gheskio (INLR) CRS
RECRUITINGPort-au-Prince, Haiti
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Liverpool Hospital
RECRUITINGSydney, Australia
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McGill University Health Centre
RECRUITINGMontreal, Quebec, H3A 0G4, Canada
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National Referral University Hospital for Pneumo-physiology
ACTIVE_NOT_RECRUITINGCotonou, Benin
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New York City Bureau of TB Control
RECRUITINGNew York, New York, 11201, United States
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New York Harbor Healthcare System
RECRUITINGManhattan, New York, 10001, United States
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Paramatta Chest
RECRUITINGSydney, Australia
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Royal Prince Alfred Hospital
RECRUITINGSydney, Australia
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San Antonio VA
ACTIVE_NOT_RECRUITINGSan Antonio, Texas, 78201, United States
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Seattle King County Health Department
RECRUITINGSeattle, Washington, 98101, United States
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Toronto Western Hospital
RECRUITINGToronto, Ontario, M5P 1N5, Canada
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Washington DC VA Medical Center
RECRUITINGWashington D.C., District of Columbia, 20001, United States
Contact
Conditions
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