Could a single day of antibiotics after appendectomy be enough?

NCT ID NCT07563933

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial compares a one-day course of antibiotics after appendix surgery to the standard five-day course in 200 children and adults with uncomplicated appendicitis. The goal is to see if the shorter course prevents infections just as well, while reducing side effects and costs. Participants will be randomly assigned to one of the two treatment durations and followed for 30 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

antibiotics (ampicillin/sulbactam)

What this could lead to

If successful, this could show that a shorter course of antibiotics after appendectomy is just as safe and effective, reducing side effects and costs.

What could go wrong

This is a relatively small trial (200 people) and has not started recruiting yet. The shorter course might prove less effective at preventing infections, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

appendicitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fayoum General Hospital

    Al Fayyum, 63511, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact