Could a single day of antibiotics after appendectomy be enough?
NCT ID NCT07563933
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial compares a one-day course of antibiotics after appendix surgery to the standard five-day course in 200 children and adults with uncomplicated appendicitis. The goal is to see if the shorter course prevents infections just as well, while reducing side effects and costs. Participants will be randomly assigned to one of the two treatment durations and followed for 30 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- antibiotics (ampicillin/sulbactam)
- What this could lead to
- If successful, this could show that a shorter course of antibiotics after appendectomy is just as safe and effective, reducing side effects and costs.
- What could go wrong
- This is a relatively small trial (200 people) and has not started recruiting yet. The shorter course might prove less effective at preventing infections, and results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Fayoum General Hospital
Al Fayyum, 63511, Egypt