Low-Dose creatine hydrochloride shows promise in small safety study
NCT ID NCT07521059
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tested the short-term safety of a low-dose creatine hydrochloride supplement (750 mg per day) in 11 healthy adults over 28 days. The goal was to see if this more soluble form of creatine is safe at lower doses than typical creatine supplements. No serious side effects were reported, but the study was very small and had no placebo group, so more research is needed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
creatine hydrochloride (a dietary supplement)
What this could lead to
If successful, this could support the safe use of low-dose creatine hydrochloride as a more efficient alternative to standard creatine supplements.
What could go wrong
This is a very small, early pilot study with only 11 healthy adults and no comparison group. Larger studies are needed to confirm safety and effectiveness.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Princeton Consumer Research
Raritan, New Jersey, 08869, United States