New combo therapy aims to shrink rectal tumors before surgery

NCT ID NCT07448077

First seen Mar 21, 2026 · Last updated May 14, 2026 · Updated 9 times

Summary

This study tests whether adding the drug enlonstobart to short-course radiotherapy and chemotherapy can help shrink tumors more effectively in people with a certain type of advanced rectal cancer (pMMR). About 128 adults will receive either the standard treatment or the new combination before surgery. The main goal is to see if the cancer completely disappears or responds well.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for EFFICACY AND SAFETY OF SHORT-COURSE RADIOTHERAPY IN TOTAL NEOADJUVANT THERAPY COMBINED WITH ENLONSTOBART FOR PMMR LOCALLY ADVANCED RECTAL CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

Explore the condition pages connected to this study.