New vaccine aims to stop deadly diarrhea in kids

NCT ID NCT07666750

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new vaccine (IP-QSV) designed to protect against four types of Shigella bacteria, which cause severe diarrhea. The trial will include 370 healthy adults, children, and infants in Mali. Researchers will check if the vaccine is safe and triggers a strong immune response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Quadrivalent Shigella vaccine (IP-QSV) – a shot that targets four types of Shigella bacteria
What this could lead to
If successful, this could lead to a vaccine that protects against Shigella infection, a major cause of severe diarrhea in children.
What could go wrong
This is an early (Phase 1/2a) study, so the vaccine may not prove safe or effective. Results are limited to a specific region and may not apply elsewhere.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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