New vaccine aims to stop deadly diarrhea in kids

NCT ID NCT07666750

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new vaccine (IP-QSV) designed to protect against four types of Shigella bacteria, which cause severe diarrhea. The trial will include 370 healthy adults, children, and infants in Mali. Researchers will check if the vaccine is safe and triggers a strong immune response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Quadrivalent Shigella vaccine (IP-QSV) – a shot that targets four types of Shigella bacteria

What this could lead to

If successful, this could lead to a vaccine that protects against Shigella infection, a major cause of severe diarrhea in children.

What could go wrong

This is an early (Phase 1/2a) study, so the vaccine may not prove safe or effective. Results are limited to a specific region and may not apply elsewhere.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

shigellosis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••