First human test of gene therapy for deadly heart rhythm disorder

NCT ID NCT07148089

Summary

This is an early safety study testing a single dose of an experimental gene therapy called SGT-501 in people with CPVT, a rare inherited condition that causes dangerous fast heart rhythms during exercise or stress. The main goal is to see if the treatment is safe and tolerable in a small group of adults and children. Participants will be closely monitored for five years after receiving the one-time infusion.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02459, United States

    Contact Email: •••••@•••••

  • Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Paul's Hospital

    RECRUITING

    Vancouver, British Columbia, BC V6Z 1Y6, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Pennsylvania

    NOT_YET_RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.