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Spine surgery showdown: which anesthetic keeps your mind sharpest?

NCT ID NCT07378878

Knowledge-focused Sponsor: Universitas Sumatera Utara Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 20 adults having spine surgery to compare two common anesthetics—sevoflurane and propofol—and their effect on thinking and memory afterward. Participants took a simple mental test before surgery and again at several points after. The goal was to see which drug might lead to less postoperative confusion, helping doctors choose safer anesthesia for spine procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Feb 2025

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patients scheduled for elective spinal surgery. Age between 18 and 65 years. ASA (American Society of Anesthesiologists) physical status I-II. Able to give informed consent. Willing to participate in all cognitive assessments (MMSE) before and after surgery. Exclusion Criteria: History of neurological disorders (e.g., dementia, stroke, epilepsy). Severe psychiatric disorders. Known allergy or contraindication to sevoflurane or propofol. History of drug or alcohol abuse. Patients undergoing emergency spinal surgery. Inability to understand or complete MMSE assessment.

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Conditions

The condition(s) this trial relates to.

Postoperative Cognitive Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Condition / focus: postoperative cognitive dysfunction (POCD) following spinal surgery

Contacts and locations

Locations

  • RSUP H. Adam Malik Medan

    Medan, North Sumatra, 20155, Indonesia