Could a rectal treatment save kids with severe malaria in remote villages?
NCT ID NCT06806956
First seen Feb 01, 2026 · Last updated May 17, 2026 · Updated 17 times
Summary
This study looks at whether giving a rectal medicine (rectal artesunate) followed by a 3-day course of artemisinin-based combination therapy (ACT) works as well as the standard injectable treatment for severe malaria in children aged 6 months to 5 years. It involves over 2,000 children in Zambia and the Democratic Republic of Congo, especially those who cannot easily reach a hospital. The goal is to find a practical, life-saving option for remote settings where injections are not available.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Tropical Diseases Research Centre
Ndola, Copperbelt, 10101, Zambia
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University of Kinshasa
Kinshasa, Kinshasa City, Democratic Republic of the Congo
Conditions
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