Could a tiny neck implant help repair MS-damaged nerves?

NCT ID NCT06796504

First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 5 times

Summary

This study tests a small device implanted on the vagus nerve in the neck to see if it can help repair myelin (the protective coating around nerves) in people with relapsing-remitting multiple sclerosis. About 60 adults aged 22–50 will take part. Two-thirds will receive active stimulation, and one-third will receive no stimulation at first, then switch to active after 48 weeks. The main goal is to check safety and any signs of nerve repair.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Johns Hopkins School of Medicine

    RECRUITING

    Baltimore, Maryland, 21287, United States

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • Minnesota Center for Multiple Sclerosis

    RECRUITING

    Plymouth, Minnesota, 55446, United States

  • Shepherd Center

    RECRUITING

    Atlanta, Georgia, 30309, United States

  • The University of Texas Health Science Center at Houston

    RECRUITING

    Houston, Texas, 77030, United States

  • The University of Texas at Austin

    RECRUITING

    Austin, Texas, 78712, United States

  • UW Medicine Multiple Sclerosis Center-Northwest

    RECRUITING

    Seattle, Washington, 98133, United States

  • University of California Irvine Center for Clinical Research

    RECRUITING

    Irvine, California, 92617, United States

  • West Virginia University

    RECRUITING

    Morgantown, West Virginia, 26506, United States

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