Engineered immune cells take aim at Hard-to-Treat leukemia

NCT ID NCT06325748

First seen Feb 13, 2026 · Last updated May 16, 2026 · Updated 12 times

Summary

This early-phase study tests SENTI-202, a ready-made immune cell therapy, in people with certain blood cancers (like AML and MDS) that have come back or not responded to treatment. The therapy uses specially designed natural killer (NK) cells to find and attack cancer cells while sparing healthy ones. The main goals are to check safety and find the best dose, with a small group of 21 participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Colorado Blood Cancer Institute

    Denver, Colorado, 80218, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Mayo Clinic

    Jacksonville, Florida, 32224, United States

  • Methodist Healthcare

    San Antonio, Texas, 78229, United States

  • Peter MacCallum Cancer Center

    Melbourne, Victoria, 3000, Australia

  • Royal Prince Alfred Hospital

    Camperdown, New South Wales, 2050, Australia

  • TriStar Bone Marrow Transplant

    Nashville, Tennessee, 37203, United States

  • UCLA Medical Center

    Los Angeles, California, 90095, United States

Conditions

Explore the condition pages connected to this study.