New gel could shrink rare skin bumps in kids and adults
NCT ID NCT06239480
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 3 trial is testing a gel containing rapamycin (QTORIN 3.9%) for people aged 3 and older with microcystic lymphatic malformations, a rare condition causing fluid-filled bumps on the skin. About 40 participants will apply the gel daily for 24 weeks to see if it improves the appearance and severity of the bumps. The study is currently active but not recruiting, and participants may continue treatment beyond 24 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
QTORIN 3.9% rapamycin anhydrous gel (a topical medication applied to the skin)
What this could lead to
If successful, this gel could offer a non-invasive treatment option to reduce the size and severity of microcystic lymphatic malformations, potentially improving symptoms and quality of life.
What could go wrong
This is a small, early-phase 3 study with only 51 participants, so results may not apply to everyone. The gel may cause skin irritation or not work for all types of lymphatic malformations.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30342, United States
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Children's Hospital of Orange County
Irvine, California, 92612, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Cincinnati Children's Hospital
Cincinnati, Ohio, 45229, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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Minnesota Clinical Study Center
New Brighton, Minnesota, 55112, United States
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Penn State Hershey Medical Center
Hershey, Pennsylvania, 17033, United States
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Stanford University
Palo Alto, California, 94305, United States
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Texas Children's Hospital
Houston, Texas, 77030, United States
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University of North Carolina
Chapel Hill, North Carolina, 27516, United States
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University of Texas, Dell Children's
Austin, Texas, 78723, United States
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University of Utah Health
Salt Lake City, Utah, 84113, United States
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Vanderbilt Children's Hospital
Nashville, Tennessee, 37232, United States
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Vascular Birthmark Institute
New York, New York, 10016, United States
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