New gel could ease rare skin condition in phase 3 trial

NCT ID NCT06239480

First seen Mar 29, 2026 · Last updated Apr 29, 2026 · Updated 4 times

Summary

This study tests a gel called QTORIN 3.9% rapamycin on people aged 3 and older with microcystic lymphatic malformations, a rare skin condition causing fluid-filled bumps. The main goal is to see if the gel improves the condition after 24 weeks of daily use. About 51 participants will apply the gel at home, and doctors will check their skin regularly. This is a phase 3 trial, meaning it's the final step before seeking approval for wider use.

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Contacts and locations

Locations

  • Children's Healthcare of Atlanta

    Atlanta, Georgia, 30342, United States

  • Children's Hospital of Orange County

    Irvine, California, 92612, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Cincinnati Children's Hospital

    Cincinnati, Ohio, 45229, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Minnesota Clinical Study Center

    New Brighton, Minnesota, 55112, United States

  • Penn State Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • Stanford University

    Palo Alto, California, 94305, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27516, United States

  • University of Texas, Dell Children's

    Austin, Texas, 78723, United States

  • University of Utah Health

    Salt Lake City, Utah, 84113, United States

  • Vanderbilt Children's Hospital

    Nashville, Tennessee, 37232, United States

  • Vascular Birthmark Institute

    New York, New York, 10016, United States

Conditions

Explore the condition pages connected to this study.