New drug cocktail offers hope for kids with relapsed leukemia
NCT ID NCT04898894
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests two drugs, selinexor and venetoclax, given together with standard chemotherapy for children and young adults whose acute myeloid leukemia (AML) has returned or not responded to treatment. The main goal is to find the safest dose and see how well the combination works at putting the cancer into remission. About 37 participants will be enrolled at St. Jude Children's Research Hospital.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Childrens Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Cook Children's Medical Center
Fort Worth, Texas, 76104, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Memorial Sloan-Kettering Cancer Center
New York, New York, 10065, United States
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Rady Children's Hospital-San Diego
San Diego, California, 92123, United States
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St. Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
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UT Southwestern/Simmons Cancer Center
Dallas, Texas, 75390, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States