Lower radiation, same hope: new drug combo aims to tame lymphoma with fewer side effects

NCT ID NCT07554482

First seen May 02, 2026 · Last updated May 23, 2026 · Updated 4 times

Summary

This study tests whether adding the drug selinexor to a lower dose of radiation (40 Gy) can work as well as standard high-dose radiation for early-stage NK/T-cell lymphoma, while causing fewer side effects like mouth sores and dry mouth. About 34 adults with untreated stage I-II disease will receive chemotherapy first, then the drug plus reduced radiation. The goal is to see if this approach keeps the cancer under control without the need for lifelong medication.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tongren Hospital, Capital Medical University

    Beijing, 100730, China

Conditions

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