New drug duo targets Tough-to-Treat blood cancer

NCT ID NCT07447817

Summary

This study is testing whether a combination of two drugs, pacritinib and selinexor, can help control myelofibrosis in patients who have not yet tried a common type of treatment (JAK inhibitors) and who have low red blood cell and platelet counts. The main goals are to see if the treatment safely shrinks the enlarged spleen and improves patients' symptoms and blood counts. About 26 adults with intermediate or high-risk disease will participate.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

    Contact

  • The University of Kansas Cancer Center-Westwood

    Westwood, Kansas, 66205, United States

    Contact

  • Wake Forest Baptist Health Comprehensive Cancer Center

    Winston-Salem, North Carolina, 27157, United States

    Contact

Conditions

Explore the condition pages connected to this study.