Next-Gen mRNA flu shot passes first safety check in humans

NCT ID NCT06125691

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 28 times

Summary

This early-stage study tested a new type of seasonal flu vaccine called ARCT-2138, which uses self-amplifying mRNA technology to potentially provide stronger protection. Researchers gave the vaccine to 139 healthy adults aged 18-49 and 65-85 to check for side effects and measure immune responses. The goal was to find the safest and most effective dose before moving to larger trials.

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Contacts and locations

Locations

  • Emeritus Research Camberwell

    Melbourne, Victoria, 3124, Australia

  • Nucleus Network Brisbane Clinic

    Brisbane, Queensland, Australia

Conditions

Explore the condition pages connected to this study.