Can a blood vessel drug ease Raynaud's in scleroderma?
NCT ID NCT02260557
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 2 trial tested whether selexipag, a drug that opens blood vessels, can reduce the number of Raynaud's attacks in adults with systemic sclerosis. 74 participants took either selexipag or a placebo twice daily. The main goal was to see if the drug lowered weekly attack frequency.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
selexipag
What this could lead to
If it works, this could point toward a new treatment to reduce the number of Raynaud's attacks in people with systemic sclerosis.
What could go wrong
This is an early Phase 2 trial with only 74 people, so results may not be conclusive. The drug may not reduce attacks more than placebo, and side effects are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Investigator Site
Grenoble, 38043, France
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Investigator Site
Lille, 59037, France
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Investigator Site
Nantes, 44093, France
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Investigator Site
Paris, 75679, France
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Investigator Site
Strasbourg, 67200, France
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Investigator Site
Bad Nauheim, 61231, Germany
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Investigator Site
Berlin, 10117, Germany
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Investigator Site
Cologne, 50937, Germany
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Investigator Site
Erlangen, 91054, Germany
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Investigator Site
Magdeburg, 39120, Germany
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Investigator Site
Mainz, 55131, Germany
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Investigator Site
Bath, BA11RL, United Kingdom
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Investigator Site
Leeds, LS74SA, United Kingdom
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Investigator Site
Liverpool, L97AL, United Kingdom
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Investigator Site
London, NW32QG, United Kingdom
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Investigator Site
Salford, M55AP, United Kingdom