New drug trial aims to stop liver disease from worsening

NCT ID NCT06051617

Recruiting now Disease control Sponsor: Gilead Sciences Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a drug called seladelpar can help prevent serious liver problems in people with primary biliary cholangitis (PBC) who have early-stage scarring (cirrhosis). About 318 participants will be randomly assigned to receive either the study drug or a placebo pill to see which group has fewer serious health events like liver failure or the need for a transplant. The main goal is to see if the drug can help people live longer without these major complications.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

A.O.U. Pisana, U.O. Epatologia
RECRUITING

Pisa, 56124, Italy
A.O.U.P. Paolo Giaccone , U.O.C di Gastroeneterologia
RECRUITING

Palermo, 90127, Italy
AES - AS - Glenny Corp. S.A. Buenos Aires
RECRUITING

Buenos Aires, C1430, Argentina
AP-HP Hopital Henri Mondor
RECRUITING

Paris, 94000, France
ASST Santi Paolo Carlo, S.C. Medicina ad Indirizzo Epatologico e Gastroenterologico
RECRUITING

Milan, 20142, Italy
Aarhus Universitetshospital
RECRUITING

Aarhus, 8200, Denmark
Adana City Training and Research Hospital
RECRUITING

Adana, 1370, Turkey (Türkiye)
Alfred Hospital
RECRUITING

Melbourne, Victoria, 3004, Australia
American Research Corporation
RECRUITING

San Antonio, Texas, 78215, United States
Ankara Bilkent City Hospital
RECRUITING

Ankara, 06800, Turkey (Türkiye)
Asan Medical Center
RECRUITING

Seoul, 05505, South Korea
Azienda Ospedaliero-Universitaria di Modena - Ospedale Civile di Baggiovara
RECRUITING

Modena, 41126, Italy
BIOCINETIC Ltda
RECRUITING

Santiago, 8330336, Chile
Beijing Ditan Hospital, Capital Medical University
RECRUITING

Beijing, 100015, China
Beijing Friendship Hospital, Capital Medical University
RECRUITING

Beijing, 100050, China
Beijing Youan Hospital, Capital Medical University
RECRUITING

Beijing, 100000, China
Beth Israel Deaconess Medical Center
RECRUITING

Boston, Massachusetts, 02215, United States
Buenos Aires Mácula
RECRUITING

Buenos Aires, C1061, Argentina
C.H. Regional Reina Sofia - PPDS
RECRUITING

Córdoba, 14004, Spain
CHRU de Nancy - Hôpitaux de Brabois
RECRUITING

Vandœuvre-lès-Nancy, 54500, France
CHU de Strasbourg - Nouvel Hôpital Civil
RECRUITING

Strasbourg, 67000, France
CHU-Montpellier-Hopital St Eloi
RECRUITING

Montipellier, 34295, France
CINME S.A. - Centro de Investigaciones Metabólicas
RECRUITING

Recoleta, C1118AAT, Argentina
California Liver Research Institute
RECRUITING

Pasadena, California, 91105, United States
California Pacific Medical Center - Sutter Pacific Medical Foundation
RECRUITING

San Francisco, California, 94109, United States
Cedar Sinai Medical Center
RECRUITING

Los Angeles, California, 90048, United States
Centre Hospitalier de l'Universite de Montreal
RECRUITING

Montreal, H2L 4M1, Canada
Centro De Investigacion Y Gastroenterogia, S.C.
RECRUITING

México, 76806, Mexico
Centro de Investigación y Prevención Cardiovascular
RECRUITING

Buenos Aires, C1061, Argentina
Centro de Investigación y Prevención Cardiovascular
RECRUITING

La Serena, 1720506, Chile
Chang Gung Medical Foundation Kaohsiung Chang Gung Memorial Hospital
RECRUITING

Kaohsiung City, 83301, Taiwan
Chang Gung Memorial Hospital, Linkou
RECRUITING

Taoyuan District, 33305, Taiwan
Changi General Hospital
RECRUITING

Singapore, 529889, Singapore
Charité Campus Virchow-Klinikum-Augustenburger Platz 1
RECRUITING

Berlin, 13353, Germany
Chonnam National University Hospital
RECRUITING

Gwangju, 61455, South Korea
Clinica de Higado y Gastroenterologia Integral, S.C.
RECRUITING

Cuernavaca, 62170, Mexico
Clinical Research Chile SpA - PPDS
RECRUITING

Valdivia, 5110683, Chile
Complexo Hospitalario Universitario De Santiago
RECRUITING

A Coruña, 15706, Spain
Connie Frank Transplant Center at UCSF
RECRUITING

San Francisco, California, 94143, United States
Consultorio Medico - Distrito Federal
RECRUITING

Mexico City, 6700, Mexico
Consultorios Médicos Dr. Doreski - PPDS
RECRUITING

Buenos Aires, 1426, Argentina
Covenant Metabolic Specialists, LLC
RECRUITING

Fort Myers, Florida, 33912, United States
Covenant Metabolic Specialists, LLC
RECRUITING

Sarasota, Florida, 33912, United States
DIM Clinica Privada
RECRUITING

Ramos Mejía, 1704, Argentina
Diex Recherche - Québec - PPDS
RECRUITING

Québec, G1V 4T3, Canada
East Suffolk and North Essex NHS Foundation Trust, Ipswich Hospital
RECRUITING

Ipswich, IP4 5PD, United Kingdom
Ege University
RECRUITING

Izmir, 35040, Turkey (Türkiye)
Evangelismos General Hospital
RECRUITING

Athens, 106 76, Greece
FAICIC
RECRUITING

Veracruz, 91900, Mexico
Fakultni nemocnice Ostrava
RECRUITING

Ostrava, 70852, Czechia
Flinders Medical Center
RECRUITING

Adelaide, South Australia, 5042, Australia
Florida Research Institute
RECRUITING

Tampa, Florida, 34211, United States
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
RECRUITING

Milan, 20122, Italy
GI Research Institute Foundation
RECRUITING

Vancouver, V6G 2Z6, Canada
Gastro One
RECRUITING

Cordova, Tennessee, 38018, United States
Gastroenterologisch - Hepatologisches MVZ Kiel GmbH
RECRUITING

Kiel, 24146, Germany
Gaziantep University Medical Faculty Sahinbey Research and Practice Hospital
RECRUITING

Gaziantep, 27630, Turkey (Türkiye)
General Hospital of Thessaloniki ''Hippokratio''
RECRUITING

Thessaloniki, 546 41, Greece
Guizhou Provincial People's Hospital
RECRUITING

Guiyang, 550002, China
Henan Provincial People's Hospital
RECRUITING

Zhengzhou, 450003, China
Henry Ford Medical Center - Columbus
RECRUITING

Detroit, Michigan, 48202, United States
Higea S.A.
RECRUITING

Mendoza, M5500, Argentina
Hopital Saint Antoine, Assistance Publique-Hopitaux de Paris
RECRUITING

Paris, 75012, France
Hospices Civils de Lyon (HCL) - Hopital de la Croix-Rousse
RECRUITING

Lyon, 69317, France
Hospital Clinic de Barcelona
RECRUITING

Barcelona, 08036, Spain
Hospital Italiano de Buenos Aires
RECRUITING

Buenos Aires, 1181, Argentina
Hospital Provincial Del Centenario
RECRUITING

Rosario, 2000, Argentina
Hospital Universitario Fundacion Alcorcon
RECRUITING

Alcorcón, 28925, Spain
Hospital Universitario Germans Trias i Pujol
RECRUITING

Badalona, 08916, Spain
Hospital Universitario Marques de Valdecilla
RECRUITING

Santander, 39008, Spain
Hospital Universitario Vall d'Hebron-VIHR
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario Virgen de la Victoria
RECRUITING

Málaga, 29010, Spain
Hospital Universitario Virgen del Rocio - PPDS
RECRUITING

Seville, 41010, Spain
Hospital del Mar
RECRUITING

Barcelona, 08003, Spain
Hull Royal Infirmary
RECRUITING

Hull, HU32JZ, United Kingdom
Hôpital Claude Huriez-Lille-1 Place de Verdun
RECRUITING

Lille, 59000, France
ID Clinic Arkadiusz Pisula
RECRUITING

Mysłowice, 41-400, Poland
IRCCS Saverio de Bellis-UOSD "Epatopatie"
RECRUITING

Castellana Grotte, 70013, Italy
Institutul Clinic Fundeni
RECRUITING

Bucharest, 022328, Romania
Kaohsiung Medical University Hospital
RECRUITING

Kaohsiung City, 80756, Taiwan
Katip Celebi University
RECRUITING

Karabağlar, 35150, Turkey (Türkiye)
King's College Hospital
RECRUITING

London, SE5 9RS, United Kingdom
Klinikum Wels-Grieskirchen GmbH - Standort Wels
RECRUITING

Wels, 4600, Austria
Kocaeli University Medical Faculty Hospital
RECRUITING

Kocaeli, 41380, Turkey (Türkiye)
Korea University Guro Hospital
RECRUITING

Seoul, 08308, South Korea
Krankenhaus der Barmherzigen Brüder
RECRUITING

Vienna, 1020, Austria
Kyungpook National University Hospital
RECRUITING

Daegu, 41944, South Korea
Landeskrankenhaus Hall
RECRUITING

Hall in Tirol, 6060, Austria
Liver Institute Northwest
RECRUITING

Seattle, Washington, 98105, United States
Liver Unit, institute of Gasteroenterology and Liver Diseases
RECRUITING

Jerusalem, 91120, Israel
Marmara University Pendik Training and Research Hospital
RECRUITING

Pendik, 34899, Turkey (Türkiye)
Maryview Hospital LLC d/b/a Bon Secours Liver Institute of Hampton Roads
RECRUITING

Newport News, Virginia, 23602, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
MedStar Health Research Institute / MedStar Georgetown Transplant Institute at Fairfax
RECRUITING

Fairfax, Virginia, 22031, United States
Medizinische Universität Wien
RECRUITING

Vienna, 1090, Austria
Mengchao Hepatobiliary Hospital of Fujian Medical University
RECRUITING

Fuzhou, China
Mercy Medical Center
RECRUITING

Baltimore, Maryland, 21202, United States
Mersin Universitesi Tip Fakultesi Hastanesi
RECRUITING

Mersin, 33110, Turkey (Türkiye)
Monash Health, Monash Medical Centre
RECRUITING

Clayton, Victoria, 3168, Australia
Mount Sinai
RECRUITING

New York, New York, 10029, United States
NYU Langone Health
RECRUITING

New York, New York, 10016, United States
National Cheng Kung University Hospital
RECRUITING

Tainan, 70403, Taiwan
National Taiwan University Hospital
RECRUITING

Taipei, 10002, Taiwan
Northern Health
RECRUITING

Epping, Victoria, 3076, Australia
Northwell Health Center for Liver Disease and Transplantation
RECRUITING

Manhasset, New York, 11030, United States
Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States
OM Research LLC
RECRUITING

Lancaster, California, 93534, United States
Oaxaca Site Management Organization - Hospital - OSMO - PPDS
RECRUITING

Oaxaca City, 71256, Mexico
Ochsner Clinic Foundation
RECRUITING

Jefferson, Louisiana, 70121, United States
Ospedale Casa Sollievo Della Sofferenza IRCCS
RECRUITING

San Giovanni Rotondo, 71013, Italy
Ottawa Hospital
RECRUITING

Ottawa, K1H 8L6, Canada
PROACTIVE CR MEXICO SA de CV
RECRUITING

Irapuato, 36650, Mexico
Penn State Health Milton S. Hershey Medical Center
RECRUITING

Hershey, Pennsylvania, 17033, United States
Piedmont Atlanta Hospital / Piedmont Transplant Institute
RECRUITING

Atlanta, Georgia, 30309, United States
Pinnacle Clinical Research, PLLC
RECRUITING

San Antonio, Texas, 78229, United States
PlanetMed SP. z. o. o
RECRUITING

Wroclaw, 52-210, Poland
Pontificia Universidad Católica de Chile
RECRUITING

Santiago, 8320000, Chile
Prince of Wales Hospital - Hong Kong
RECRUITING

Hong Kong, 000, Hong Kong
Princess Alexandra Hospital
RECRUITING

Queensland, Queensland, 4102, Australia
Princess Margaret Hospital - Hong Kong
RECRUITING

Hong Kong, Hong Kong
Pusan National University Hospital
RECRUITING

Busan, 49241, South Korea
Queen Mary Hospital - PPDS
RECRUITING

Hong Kong, 999077, Hong Kong
RESEARCH Site s.r.o
RECRUITING

Pilsen, 301 00, Czechia
Rize Recep Tayyip Erdogan University Training and Research Hospital
RECRUITING

Rize Merkez, 53020, Turkey (Türkiye)
Royal Free Hospital
RECRUITING

London, NW2 2QG, United Kingdom
SCPMG/Kaiser Permanente Los Angeles Medical Center
RECRUITING

Los Angeles, California, 90027, United States
Samsung Medical Center
RECRUITING

Seoul, 6351, South Korea
Schiff Center for Liver Diseases/University of Miami
RECRUITING

Miami, Florida, 33136, United States
Seoul National University Bundang Hospital
RECRUITING

Seongnam, 13620, South Korea
Seoul National University Hospital
RECRUITING

Seoul, 3080, South Korea
Severance Hospital, Yonsei University Health System
RECRUITING

Seoul, 3722, South Korea
Sheffield teaching hospital NHS foundation trust
RECRUITING

Sheffield, S10 2JF, United Kingdom
Singapore General Hospital (SGH)
RECRUITING

Singapore, 308433, Singapore
Soma Clinical Trials
RECRUITING

Denison, Texas, 75020, United States
Somogy Varmegyei Kaposi Mor Oktato Korhaz
RECRUITING

Kaposvár, 7400, Hungary
St. Joseph's Hospital and Medical Center - 350 W. Thomas
RECRUITING

Phoenix, Arizona, 85013, United States
Stanford University
RECRUITING

Redwood City, California, 94063, United States
Tan Tock Seng Hospital
RECRUITING

Singapore, 308433, Singapore
The Catholic University of Korea, Seoul St. Mary's Hospital
RECRUITING

Seoul, 6591, South Korea
The Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44195, United States
The First Affiliated Hospital of Anhui Medical University
RECRUITING

Hefei, 230032, China
The First Affiliated Hospital of PLA Air Force Medical University
RECRUITING

Xi'an, 710032, China
The First Affiliated Hospital of Xi'an Jiaotong University
RECRUITING

Xi'an, 710061, China
The First Affiliated Hospital of Xinjiang Medical University
RECRUITING

Ürümqi, 830054, China
The First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING

Zhejiang, 310009, China
The Liver Institute at Methodist Dallas Medical Center
RECRUITING

Dallas, Texas, 75203, United States
The Ohio State University Medical Center
RECRUITING

Columbus, Ohio, 43210, United States
The Royal London Hospital
RECRUITING

London, E1 1BB, United Kingdom
The Second Affiliated Hospital of Chongqing Medical University
RECRUITING

Chongqing, 401336, China
The Second Hospital of Nanjing
RECRUITING

Nanjing, 210003, China
The Third Affiliated Hospital, Sun Yat-Sen University
RECRUITING

Guangzhou, 510630, China
The Third People's Hospital of Zhenjiang
RECRUITING

Zhenjiang, 212021, China
Thomas Jefferson University
RECRUITING

Philadelphia, Pennsylvania, 19107, United States
UPMC Center for Liver Diseases
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
UZ Antwerpen
RECRUITING

Edegem, 2650, Belgium
UZ Gent
RECRUITING

Ghent, 9000, Belgium
UZ Leuven - PPDS
RECRUITING

Leuven, 3000, Belgium
Uludag University Medical Faculty
RECRUITING

Görükle, 16059, Turkey (Türkiye)
Union Hospital Tongji Medical College Huazhong University of Science and Technology
RECRUITING

Wuhan, 430030, China
Universitatsklinikum des Saarlandes
RECRUITING

Homburg, 66421, Germany
University General Hospital of Larissa
RECRUITING

Larissa, 41 110, Greece
University Health System - East Jefferson General Hospital Campus
RECRUITING

New Orleans, Louisiana, 70112, United States
University Hosptials Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States
University Of Iowa Hospitals And Clinics
RECRUITING

Iowa City, Iowa, 52242, United States
University of Alberta
RECRUITING

Edmonton, T6G 2B7, Canada
University of Calgary
RECRUITING

Calgary, T2N 4Z6, Canada
University of California, Davis Medical Center
RECRUITING

Sacramento, California, 95817, United States
University of Chicago Medical Center
RECRUITING

Chicago, Illinois, 60637, United States
University of Louisville, Clinical Trials Unit
RECRUITING

Louisville, Kentucky, 40202, United States
University of Pennsylvania Perelman Center for Advanced Medicine
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Rochester Medical Center - Strong Memorial Hospital
RECRUITING

Rochester, Minnesota, 14642, United States
University of Texas Southwestern Medical Center, Professional Office Building One
RECRUITING

Dallas, Texas, 75390, United States
Universitätsspital Bern
RECRUITING

Bern, 3010, Switzerland
Universitätsspital Zürich
RECRUITING

Zurich, 8091, Switzerland
VCU Health Clinical Research Services Unit (CRSU)
RECRUITING

Richmond, Virginia, 23298, United States
Wake Forest Baptist Medical Center
RECRUITING

Winston-Salem, North Carolina, 27157, United States
Walter Reed National Military
RECRUITING

Bethesda, Maryland, 20889, United States
West China Hospital of Sichuan University
RECRUITING

Chengdu, 610047, China

Conditions

Explore the condition pages connected to this study.

PRIMARY BILIARY CHOLANGITIS