Knee cartilage patch study halted – early results inconclusive

NCT ID NCT04537013

First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 25 times

Summary

This study tested whether a special collagen patch (Chondro-Gide®) placed over large knee cartilage injuries could help people recover as well as standard microfracture surgery for smaller injuries. The study planned to enroll 82 people aged 18–55 with knee cartilage damage, but it was terminated early. The main goal was to see if the patch improved pain and function without serious side effects.

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Contacts and locations

Locations

  • Emory Sports Medicine Complex

    Johns Creek, Georgia, 30097, United States

  • Fraser Orthopaedic Institute

    New Westminster, British Columbia, V3L 0E4, Canada

  • Gelenkzentrum Mittelrhein GmbH

    Mayen, Mayen, 63 D-56727, Germany

  • Hamilton Health Sciences

    Hamilton, Ontario, L8N 3Z5, Canada

  • Orthopaedic Foundation

    Stamford, Connecticut, 06905, United States

  • Orthopädische Chirurgie München

    München, 81369, Germany

  • Regio Kliniken GmbH

    Pinneberg, Schleswig-Holstein, 25421, Germany

  • Sportklinik Ravensburg

    Ravensburg, Germany

  • St. Joseph's Healthcare Hamilton

    Hamilton, Ontario, L8N 4A6, Canada

  • Sunnybrook Research Institute (SRI)

    Toronto, Ontario, M4N 3M5, Canada

  • The MORE Foundation

    Phoenix, Arizona, 85023, United States

  • University Hospital Regensburg

    Regensburg, Germany

  • University of Calgary

    Calgary, CGY, T2N5A1, Canada

  • University of Toronto Orthopaedics

    Toronto, TOR, M5S 1B2, Canada

  • Universitätsklinikum Schleswig Holstein Campus Lübeck

    Lübeck, Germany

Conditions

Explore the condition pages connected to this study.