New drug aims to tame painful muscle condition and cut steroid dependence

NCT ID NCT05767034

Completed Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study tested whether adding a drug called secukinumab to standard steroid treatment helps people with polymyalgia rheumatica (PMR) who recently had their symptoms return. About 381 adults aged 50+ received either secukinumab or a placebo injection alongside a tapering steroid course for a year. The main goal was to see if the combination kept patients in remission longer and allowed them to use less steroids overall.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

AZ Arthritis and Rheumtlgy Rsh PLLC

Phoenix, Arizona, 85032, United States
Accurate Clinical Research Inc

San Antonio, Texas, 78229, United States
Advanced Rheumatology of Houston

Spring, Texas, 77382, United States
Arizona Arthritis and Rheumatology Associates PLLC

Avondale, Arizona, 85392, United States
Center for Rheumatology Research

West Hills, California, 91307, United States
Clinical Research Inst of MI

Saint Clair Shores, Michigan, 48081, United States
DM Clinical Research

Houston, Texas, 77070, United States
Dartmouth Hitchcock Medical Center

Lebanon, New Hampshire, 03756, United States
Kansas City Physician Partners

Kansas City, Missouri, 64111, United States
Klein and Associates

Hagerstown, Maryland, 21740, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Millennium Clinical Trials

Westlake Village, California, 91361, United States
Novartis Investigative Site

Caba, Buenos Aires, C1119ACN, Argentina
Novartis Investigative Site

Quilmes, Buenos Aires, B1878GEG, Argentina
Novartis Investigative Site

Buenos Aires, C1055AAF, Argentina
Novartis Investigative Site

Parramatta, New South Wales, 2150, Australia
Novartis Investigative Site

Southport, Queensland, 4215, Australia
Novartis Investigative Site

Heidelberg Heights, Victoria, 3081, Australia
Novartis Investigative Site

Leuven, 3000, Belgium
Novartis Investigative Site

Liège, 4000, Belgium
Novartis Investigative Site

Porto Alegre, Rio Grande do Sul, 90480-000, Brazil
Novartis Investigative Site

São Paulo, São Paulo, 04038-002, Brazil
Novartis Investigative Site

São Paulo, 01409-902, Brazil
Novartis Investigative Site

Québec, Quebec, G1V 3M7, Canada
Novartis Investigative Site

Viña del Mar, Región de Valparaíso, 2531172, Chile
Novartis Investigative Site

Santiago, Santiago Metropolitan, 7500571, Chile
Novartis Investigative Site

Santiago, Santiago Metropolitan, 8380465, Chile
Novartis Investigative Site

Santiago, Santiago Metropolitan, 8420383, Chile
Novartis Investigative Site

Barranquilla, Atlántico, 080002, Colombia
Novartis Investigative Site

Barranquilla, Atlántico, 080020, Colombia
Novartis Investigative Site

Bogota, Cundinamarca, 110221, Colombia
Novartis Investigative Site

Cali, Valle del Cauca Department, 760042, Colombia
Novartis Investigative Site

Prague, Czech Republic, 140 00, Czechia
Novartis Investigative Site

Brno, 638 00, Czechia
Novartis Investigative Site

Hlučín, 748 01, Czechia
Novartis Investigative Site

Prague, 128 00, Czechia
Novartis Investigative Site

Prague, 140 00, Czechia
Novartis Investigative Site

Uherské Hradiště, 686 01, Czechia
Novartis Investigative Site

Zlín, 760 01, Czechia
Novartis Investigative Site

Aarhus N, 8200, Denmark
Novartis Investigative Site

Esbjerg, 6700, Denmark
Novartis Investigative Site

Gandrup, 9362, Denmark
Novartis Investigative Site

Vejle, DK-7100, Denmark
Novartis Investigative Site

Limoges, Haute Vienne, 87000, France
Novartis Investigative Site

Toulon, Val De Marne, 83800, France
Novartis Investigative Site

Aix-en-Provence, 13616, France
Novartis Investigative Site

Brest, 29200, France
Novartis Investigative Site

Cholet, 49325, France
Novartis Investigative Site

Colmar, 68024, France
Novartis Investigative Site

Dijon, 21000, France
Novartis Investigative Site

Le Mans, 72000, France
Novartis Investigative Site

Montpellier, 34295, France
Novartis Investigative Site

Nantes, 44093, France
Novartis Investigative Site

Reims, 51092, France
Novartis Investigative Site

Strasbourg, 67000, France
Novartis Investigative Site

Toulouse, 31059, France
Novartis Investigative Site

Freiburg im Breisgau, Baden-Wurttemberg, 79106, Germany
Novartis Investigative Site

Würzburg, Bavaria, 97080, Germany
Novartis Investigative Site

Dresden, Saxony, 01307, Germany
Novartis Investigative Site

Berlin, 13125, Germany
Novartis Investigative Site

Berlin, 13353, Germany
Novartis Investigative Site

Erlangen, 91056, Germany
Novartis Investigative Site

Herne, 44649, Germany
Novartis Investigative Site

Ratingen, 40878, Germany
Novartis Investigative Site

Rendsburg, 24768, Germany
Novartis Investigative Site

Budapest, 1027, Hungary
Novartis Investigative Site

Szeged, 6725, Hungary
Novartis Investigative Site

Veszprém, 8200, Hungary
Novartis Investigative Site

Reykjavik, 101, Iceland
Novartis Investigative Site

Dublin, D03 VX82, Ireland
Novartis Investigative Site

Ramat Gan, 5265601, Israel
Novartis Investigative Site

Tel Aviv, 6423906, Israel
Novartis Investigative Site

Bolzano, BZ, 39100, Italy
Novartis Investigative Site

Milan, MI, 20100, Italy
Novartis Investigative Site

Milan, MI, 20132, Italy
Novartis Investigative Site

Milan, MI, 20157, Italy
Novartis Investigative Site

Perugia, PG, 06129, Italy
Novartis Investigative Site

Pavia, PV, 27100, Italy
Novartis Investigative Site

Reggio Emilia, RE, 42123, Italy
Novartis Investigative Site

Ichikawa, Chiba, 2728516, Japan
Novartis Investigative Site

Fukuoka, Fukuoka, 8140180, Japan
Novartis Investigative Site

Asahikawa, Hokkaido, 0708644, Japan
Novartis Investigative Site

Kita-gun, Kagawa-ken, 7610793, Japan
Novartis Investigative Site

Sagamihara, Kanagawa, 252-0392, Japan
Novartis Investigative Site

Yokohama, Kanagawa, 222-0036, Japan
Novartis Investigative Site

Nagano, Nagano, 3808582, Japan
Novartis Investigative Site

Beppu, Oita Prefecture, 8740011, Japan
Novartis Investigative Site

Kawachi-Nagano, Osaka, 5868521, Japan
Novartis Investigative Site

Osaka, Osaka, 550-0006, Japan
Novartis Investigative Site

Bunkyo Ku, Tokyo, 1138431, Japan
Novartis Investigative Site

Fuchū, Tokyo, 1838524, Japan
Novartis Investigative Site

Ōme, Tokyo, 198-0042, Japan
Novartis Investigative Site

Shimonoseki, Yamaguchi, 750-0041, Japan
Novartis Investigative Site

Chūō, Yamanashi, 409-3898, Japan
Novartis Investigative Site

Okayama, 700-8607, Japan
Novartis Investigative Site

Osaka, 5340021, Japan
Novartis Investigative Site

Beirut, 166830, Lebanon
Novartis Investigative Site

Guadalajara, Jalisco, 44650, Mexico
Novartis Investigative Site

Almelo, Overijssel, 7609 PP, Netherlands
Novartis Investigative Site

Rotterdam, South Holland, 3079 DZ, Netherlands
Novartis Investigative Site

Groningen, 9713 GZ, Netherlands
Novartis Investigative Site

Bytom, 41 902, Poland
Novartis Investigative Site

Lublin, 20-607, Poland
Novartis Investigative Site

Warsaw, 02-118, Poland
Novartis Investigative Site

Warsaw, 02-637, Poland
Novartis Investigative Site

Warsaw, 02-665, Poland
Novartis Investigative Site

Cape Town, Western Cape, 7405, South Africa
Novartis Investigative Site

Cape Town, Western Cape, 7500, South Africa
Novartis Investigative Site

Stellenbosch, Western Cape, 7600, South Africa
Novartis Investigative Site

Sabadell, Barcelona, 08208, Spain
Novartis Investigative Site

Bilbao, Bizkaia, 48013, Spain
Novartis Investigative Site

A Coruña, 15006, Spain
Novartis Investigative Site

Barcelona, 08041, Spain
Novartis Investigative Site

Madrid, 28009, Spain
Novartis Investigative Site

Seville, 41013, Spain
Novartis Investigative Site

Valencia, 46010, Spain
Novartis Investigative Site

Stockholm, SE, 113 65, Sweden
Novartis Investigative Site

Basel, 4031, Switzerland
Novartis Investigative Site

Fribourg, 1708, Switzerland
Novartis Investigative Site

Sankt Gallen, 9007, Switzerland
Novartis Investigative Site

Barnet, EN5 3DJ, United Kingdom
Novartis Investigative Site

Hull, HU3 2RW, United Kingdom
Novartis Investigative Site

Wolverhampton, WV10 0QP, United Kingdom
Paramount Med Rsrch and Consult LLC

Middleburg Heights, Ohio, 44130, United States
Precn Comprehensive Clnl Rsch Solns

San Leandro, California, 94578, United States
Prolato Clinical Research Center

Houston, Texas, 77054, United States
Providence Saint Johns Health Ctr

Santa Monica, California, 90404, United States
Rheumatology Associates of South Florida

Boca Raton, Florida, 33486, United States
Sarasota Arthritis Res Ctr

Sarasota, Florida, 34239, United States
Southeastern Rheumatology Alliance

Gainesville, Georgia, 30501, United States
Sun Valley Arthritis Center Ltd

Peoria, Arizona, 85381, United States
UF Health Cancer Center

Gainesville, Florida, 32610, United States
West Broward Rheumatology Associates Inc

Tamarac, Florida, 33321, United States

Conditions

Explore the condition pages connected to this study.

POLYMYALGIA RHEUMATICA