New hope for liver cancer patients when first treatment fails

NCT ID NCT07501351

First seen Apr 04, 2026 · Last updated Jun 14, 2026 · Updated 12 times

Summary

This study is for people with advanced liver cancer whose first treatment (bevacizumab plus sintilimab) stopped working. It compares two second-line options: adding lenvatinib to the current regimen or switching to regorafenib plus a PD-1 inhibitor. The goal is to see which approach helps patients live longer and controls the cancer better. About 80 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Sun Yat-sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, 510000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.