Can a little extra oxygen save tiny lungs during intubation?

NCT ID NCT06683599

Recruiting now Symptom relief Sponsor: Vinícius C Quintão, MD, MSc, PhD Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving infants extra oxygen through a nasal cannula during breathing tube placement (intubation) helps prevent dangerous drops in oxygen levels. About 240 infants up to 52 weeks old will be randomly assigned to receive either standard care or extra oxygen. The goal is to see if this simple addition improves first-attempt success and reduces complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: low-flow nasal supplemental oxygen
What this could lead to: If it works, this could make intubation safer for infants by reducing dangerous drops in oxygen levels.
What could go wrong: This is a relatively small, early-stage study (240 infants) and the benefit may be modest or not apply to all situations. Extra oxygen might not prevent complications in every case.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIFFICULT AIRWAY DIFFICULT AIRWAY INTUBATION NEONATE

Contacts and locations

Locations

Hospital das Clinicas HCFMUSP
RECRUITING

São Paulo, 05403000, Brazil
Perth Children's Hospital
RECRUITING

Perth, Western Australia, 6009, Australia
Uppsala University Hospital
RECRUITING

Uppsala, Sweden

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