New hope for rare disease: experimental combo targets amyloid buildup

NCT ID NCT07388602

First seen Feb 05, 2026 · Last updated May 25, 2026 · Updated 21 times

Summary

This study tests whether adding the experimental drug SCTC21C to standard chemotherapy (bortezomib, cyclophosphamide, dexamethasone) works better than chemo alone for people newly diagnosed with AL amyloidosis, a rare disease where abnormal proteins damage organs. About 90 adults with measurable disease and at least one affected organ will participate. The main goal is to see if more patients achieve a complete blood response, meaning the abnormal protein disappears from the blood.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Peking Union Medical College Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.