Promising epilepsy drug trial halted early – what we know

NCT ID NCT04873869

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental drug called NBI-921352 in people aged 2 to 21 with a rare, severe form of epilepsy caused by a change in the SCN8A gene. The goal was to see if adding this drug to their current seizure medicines could reduce how often they had seizures. The trial was stopped early, so results are limited, but it aimed to help control seizures rather than cure the condition.

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Conditions

The condition(s) this trial relates to.

developmental and epileptic encephalopathy, 13 epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's National Hospital

    Washington D.C., District of Columbia, 20010, United States

  • Cook Children's Medical Center

    Fort Worth, Texas, 76104, United States

  • UCSF Medical Center

    San Francisco, California, 94158, United States

  • University of Rochester

    Rochester, New York, 14642, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.