Can a Tumor's genes reveal the best treatment path?
NCT ID NCT02306096
First seen Aug 27, 2026 · Last updated Aug 28, 2026 · Updated 1 time
Summary
This large Swedish study collects tumor samples from 20,000 people with breast cancer to map their genetic profiles. Researchers will analyze RNA and DNA to link gene patterns with patient outcomes, such as survival and response to therapy. The goal is to develop new molecular diagnostic tests that could guide more personalized treatment decisions.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to new molecular diagnostic tests that help doctors tailor breast cancer treatment based on a tumor's genetic profile.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly test new therapies. The findings may take years to translate into clinical tools, and not all genetic markers will prove useful.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 20,000 people
The number the study aims to enrol. It can still change while the study runs.
- Start date
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Aug 2010
- Expected to finish
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Aug 2031
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All patients with suspected or confirmed diagnosis of primary breast cancer within participating hospital systems in the South Sweden Healthcare Region, Uppsala County, and Jönköping Country, Sweden. Additional hospital sites from within the Nordic countries are welcome to join.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * suspicion or confirmed diagnosis of primary breast cancer * signed informed consent Exclusion Criteria: * lack of signed informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
10 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Blekinge County Hospital
RECRUITINGKarlskrona, 37185, Sweden
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Central Hospital Kristianstad
RECRUITINGKristianstad, 29185, Sweden
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Central Hospital Växjö
RECRUITINGVaxjo, 35234, Sweden
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Hallands Hospital Halmstad
SUSPENDEDHalmstad, 30233, Sweden
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Helsingborg Hospital
RECRUITINGHelsingborg, 25187, Sweden
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Kirurgiska kliniken
SUSPENDEDJönköping, 55185, Sweden
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Skåne University Hospital
RECRUITINGLund, 22185, Sweden
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Skåne University Hospital
RECRUITINGMalmö, 20502, Sweden
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Södra Älvsborg Hospital
RECRUITINGBorås, Sweden
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Uppsala University Hospital
RECRUITINGUppsala, 75185, Sweden
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Retrospective analysis of pyrotinib in the treatment of HER2-Positive advanced breast cancer previously treated with trastuzumab and pertuzumab
- AI-Assisted opportunistic breast cancer screening using non-contrast chest CT in women undergoing health examination: a retrospective validation and prospective Single-Arm interventional study
- Single-Fraction very accelerated partial breast irradiation (sfVAPBI) in Low-Risk invasive or ductal in situ breast carcinoma - phase II multicenter trial
- Mind and body: does resilience leave a molecular mark in breast cancer?
- Which pain block works better for breast surgery?
- Can a Triple-Drug combo erase HER2-Positive breast tumors before surgery?