Could a simple magnesium spray quiet a chronic cough?
NCT ID NCT07690059
First seen Jul 08, 2026 · Last updated Jul 10, 2026 · Updated 2 times
Summary
This study tests whether a magnesium salt oral spray, called SC0032, can safely reduce coughing in adults with refractory or unexplained chronic cough—a cough that persists despite treatment or has no clear cause. Participants are randomly assigned to receive either the magnesium spray or a placebo (sodium chloride spray) for about three weeks. The main goal is to measure changes in 24-hour cough frequency using a special monitor.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- magnesium chloride oral spray
- What this could lead to
- If effective, this spray could offer a new, drug-free option to reduce coughing in people with chronic cough that doesn't respond to other treatments.
- What could go wrong
- This is a small, early-phase pilot study. The spray may not reduce cough more than placebo, and individual results may vary. Long-term safety and effectiveness are not yet known.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for REFRACTORY CHRONIC COUGH AND UNEXPLAINED CHRONIC COUGH are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Kings College Hospital
London, SE5 9RS, United Kingdom
Contact
-
Royal Brompton Hospital
London, SW3 6NP, United Kingdom
Contact
-
The Wellcome Trust-Wolfson Northern Ireland Clinical Research Facility U Floor, Belfast City Hospital
Belfast, BT9 7AB, United Kingdom
Contact