New drug trial aims to tame rare neurological disease Flare-Ups

NCT ID NCT05271409

Recruiting now Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

Summary

This study is testing whether the drug satralizumab can prevent relapses in people with MOG antibody-associated disease (MOGAD), a rare condition that causes inflammation in the brain and spinal cord. The trial will enroll 152 participants aged 12 and older who have had recent disease attacks. Participants will receive either satralizumab or a placebo to see which group has fewer relapses over time.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AOU Policlinico V. Emanuele - P.O G. Rodolico
RECRUITING

Catania, Sicily, 95123, Italy
Azienda Ospedaliera Universitaria Integrata Verona
RECRUITING

Verona, Veneto, 37134, Italy
Azienda Sanitaria Ospedaliera S. Luigi Gonzaga
RECRUITING

Orbassano, Piedmont, 10043, Italy
Baylor College of Medicine
WITHDRAWN

Houston, Texas, 77030, United States
Box Hill Hospital
WITHDRAWN

Box Hill, Victoria, 3128, Australia
Brain and Mind Research Institute
RECRUITING

Camperdown, New South Wales, 2050, Australia
CH de Bicêtre
RECRUITING

Le Kremlin-Bicêtre, 94275, France
CHU de Toulouse - Hôpital Purpan
WITHDRAWN

Toulouse, 31059, France
Centro de Pesquisas Clinicas
RECRUITING

São Paulo, São Paulo, 01228-200, Brazil
Centrum Medyczne "MEDYK"
WITHDRAWN

Rzeszów, 35-055, Poland
Chiba University Hospital
RECRUITING

Chiba, 260-8677, Japan
Children's Hospital of Eastern Ontario
RECRUITING

Ottawa, Ontario, K1H 8L1, Canada
Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44915, United States
Consultants in Neurology Ltd
WITHDRAWN

Northbrook, Illinois, 60062, United States
Duke University Medical Center
WITHDRAWN

Durham, North Carolina, 27710, United States
Fondazione IRCCS Istituto Neurologico Carlo Besta
WITHDRAWN

Milan, Lombardy, 20133, Italy
Fondazione Istituto Neurologico Mondino IRCCS
RECRUITING

Pavia, Lombardy, 27100, Italy
Hadassah University Hospital Ein Kerem
RECRUITING

Jerusalem, 9112001, Israel
Hopital Pierre Wertheimer
RECRUITING

Bron, 69677, France
Hospital Universitario Gaffree e Guinle
RECRUITING

Rio de Janeiro, 20270-004, Brazil
IRCCS Ospedale San Raffaele
ACTIVE_NOT_RECRUITING

Milan, Lombardy, 20132, Italy
Instituto de Neurologia de Curitiba
RECRUITING

Curitiba, Paraná, 81210-310, Brazil
Instituto do Cerebro do Rio Grande do Sul
RECRUITING

Porto Alegre, Rio Grande do Sul, 90610-000, Brazil
Instytut Pomnik Centrum Zdrowia Dziecka
RECRUITING

Warsaw, 04-730, Poland
John Hunter Hospital
RECRUITING

New Lambton, New South Wales, 2305, Australia
Johns Hopkins
RECRUITING

Baltimore, Maryland, 21287, United States
Juntendo University Hospital
RECRUITING

Tokyo, 113-8431, Japan
Keio University Hospital
RECRUITING

Tokyo, 160-8582, Japan
Kitasato University Hospital
RECRUITING

Kanagawa, 252-0375, Japan
Klinika Neurologii I Wydzialu Lekarskiego WUM w Warszawie
RECRUITING

Warsaw, 02-097, Poland
Klinikum Großhadern, LMU
ACTIVE_NOT_RECRUITING

Munich, 81377, Germany
Kobe University Hospital
RECRUITING

Hyōgo, 650-0017, Japan
Kyushu University Hospital
RECRUITING

Fukuoka, 812-8582, Japan
London Health Sciences Centre Uni Campus
RECRUITING

London, Ontario, N6A 5A5, Canada
MUCH - Montreal Neurological Institute & Hospital
RECRUITING

Montreal, Quebec, H3A 2B4, Canada
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Mayo Clinic - Rochester
RECRUITING

Rochester, Minnesota, 55902, United States
Mayo Clinic- Scottsdale
WITHDRAWN

Scottsdale, Arizona, 85259, United States
Medical College of Wisconsin
COMPLETED

Milwaukee, Wisconsin, 53226, United States
Medstar Georgetown University Hospital
RECRUITING

Washington D.C., District of Columbia, 20007, United States
Memorial Healthcare Institute for Neurosciences and Multiple Sclerosis
RECRUITING

Owosso, Michigan, 48867, United States
Meridian Clinical Research, LLC
WITHDRAWN

Savannah, Georgia, 31406, United States
Monash Medical Centre
RECRUITING

Clayton, Victoria, 3168, Australia
NYU Langone
RECRUITING

New York, New York, 10003, United States
National Cancer Center
RECRUITING

Goyang-si, 10408, South Korea
Nemours Children's Clinic - of the Nemours Foundation
RECRUITING

Jacksonville, Florida, 32207, United States
NeuroCure Clinical Research Center (NCRC)
ACTIVE_NOT_RECRUITING

Berlin, 10117, Germany
Neurology UKSH Campus Kiel
ACTIVE_NOT_RECRUITING

Kiel, 24105, Germany
Northwestern University
WITHDRAWN

Chicago, Illinois, 60611, United States
OhioHealth Research Institute
WITHDRAWN

Columbus, Ohio, 43214, United States
Ospedale Pediatrico Bambino Gesù
ACTIVE_NOT_RECRUITING

Rome, Lazio, 00165, Italy
Perron Institute for Neurological and Translational Science
RECRUITING

Nedlands, Western Australia, 6009, Australia
Premier Neurology
COMPLETED

Greenville, South Carolina, 29605, United States
Royal Melbourne Hospital
WITHDRAWN

Parkville, Victoria, 3050, Australia
Royal North Shore Hospital
WITHDRAWN

St Leonards, New South Wales, 2065, Australia
SPSK nr 1
ACTIVE_NOT_RECRUITING

Zabrze, 41-800, Poland
Saitama Medical Center
RECRUITING

Saitama, 350-8550, Japan
Samsung Medical Center
RECRUITING

Seoul, 06351, South Korea
Seoul National University Hospital
ACTIVE_NOT_RECRUITING

Seoul, 03080, South Korea
Southern Tohoku Medical Clinic
RECRUITING

Fukushima, 963-8052, Japan
St Vincent's Hospital Melbourne
WITHDRAWN

Fitzroy, Victoria, 3065, Australia
St. Josef-Hospital, Klinik für Neurologie
ACTIVE_NOT_RECRUITING

Bochum, 44791, Germany
Sydney Children's Hospital
RECRUITING

Randwick, New South Wales, 2031, Australia
Szpital Uniwersytecki w Krakowie
WITHDRAWN

Krakow, 30-688, Poland
The Hospital for Sick Children
RECRUITING

Toronto, Ontario, M5G 1X8, Canada
The Jikei University Hospital
RECRUITING

Tokyo, 105-8471, Japan
The University of Osaka Hospital
RECRUITING

Osaka, 565-0871, Japan
Tohoku Medical and Pharmaceutical University Hospital
RECRUITING

Miyagi, 983-8512, Japan
Tohoku University Hospital
RECRUITING

Miyagi, 980-8574, Japan
Tokyo Medical University Hospital
RECRUITING

Tokyo, 160-0023, Japan
Tokyo Women's Medical University Hospital
WITHDRAWN

Tokyo, 162-8666, Japan
Unity Health Toronto - St. Michael's Hospital
WITHDRAWN

Toronto, Ontario, M5B 1W8, Canada
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35233, United States
University of California Irvine - Manchester Pavilion
RECRUITING

Irvine, California, 92697, United States
University of Cincinnati
ACTIVE_NOT_RECRUITING

Cincinnati, Ohio, 45267, United States
University of Colorado - Anschutz Medical Campus (University of Colorado Health Sciences Center)
RECRUITING

Aurora, Colorado, 80045, United States
University of Florida College of Medicine Gainesville
RECRUITING

Gainesville, Florida, 32608, United States
Universitätsklinikum Düsseldorf
ACTIVE_NOT_RECRUITING

Düsseldorf, 40225, Germany
Universitätsklinikum Mannheim
ACTIVE_NOT_RECRUITING

Mannheim, 68167, Germany
Vestische Kinder- und Jugendklinik Datteln
RECRUITING

Datteln, 45711, Germany
Washington University School of Medicine in St. Louis
RECRUITING

St Louis, Missouri, 63110, United States
Wielospecjalistyczna Poradnia Lekarska Synapsis
RECRUITING

Katowice, 40-123, Poland

Conditions

Explore the condition pages connected to this study.

MYELIN OLIGODENDROCYTE GLYCOPROTEIN ANTIBODY-ASSOCIATED DISEASE (MOGAD)