Experimental NK cell therapy for blood cancers hits early hurdle
NCT ID NCT05839626
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tested a new drug called SAR445514, which helps the body's natural killer (NK) cells attack cancer cells in people with multiple myeloma or light-chain amyloidosis that had returned or stopped responding to other treatments. The study was terminated early, so results are limited. About 32 participants were enrolled to check safety and find the right dose.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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HOSPITAL CLINIC i PROVINCIAL BARCELONA_Site Number : 7240003
Barcelona, 08036, Spain
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Het Ziekenhuisnetwerk Antwerpen vzw - ZNA Cadix_Site Number : 0560001-1
Antwerp, 2030, Belgium
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Het Ziekenhuisnetwerk Antwerpen vzw - ZNA Middelheim_Site Number : 0560001-2
Antwerp, 2020, Belgium
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Hospital Universitario Marqués de Valdecilla_Site Number : 7240001
Santander, Cantabria, 39008, Spain
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Institut Catala d´oncologia - Badalona_Site Number : 7240002
Badalona, Catalonia, 08916, Spain
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Institut Jules Bordet_Site Number : 0560002
Anderlecht, 1070, Belgium
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Investigational Site Number : 0360001
Wollongong, New South Wales, 2500, Australia
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Investigational Site Number : 0360002
Richmond, Victoria, 3121, Australia
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Investigational Site Number : 0560001
Antwerp, 2060, Belgium
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Investigational Site Number : 2030001
Ostrava, 708 52, Czechia
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Investigational Site Number : 2030002
Brno, 625 00, Czechia
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Investigational Site Number : 3480001
Budapest, 1085, Hungary
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Investigational Site Number : 3800001
Rozzano, Lombardy, 20089, Italy
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Investigational Site Number : 8260001
Manchester, M20 4BX, United Kingdom
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Investigational Site Number : 8260002
London, NW1 2BU, United Kingdom
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Investigational Site Number : 8260003
Birmingham, B15 2TH, United Kingdom