Spit test could spot concussions in athletes

NCT ID NCT06149351

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is working on a new way to diagnose concussions in athletes using a simple saliva test. Researchers will measure specific molecules in the saliva of 80 male athletes (professional, amateur, and occasional) before, during, and after exercise. The goal is to find reliable biomarkers that can quickly and accurately identify a concussion, which is often hard to detect with standard brain scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Saliva biomarker analysis (nucleic acids and proteins)
What this could lead to
If successful, this could lead to a simple, non-invasive saliva test to quickly diagnose concussions in athletes, reducing reliance on subjective assessments.
What could go wrong
This is an early-stage observational study with only 80 participants, so results may not be generalizable. The biomarkers may not prove reliable enough for a diagnostic test.

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Conditions

The condition(s) this trial relates to.

Brain Concussion traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sys2Diag - Umr9005 Cnrs/Alcen

    RECRUITING

    Montpellier, 34184, France

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