Spit test could spot concussions in athletes

NCT ID NCT06149351

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is working on a new way to diagnose concussions in athletes using a simple saliva test. Researchers will measure specific molecules in the saliva of 80 male athletes (professional, amateur, and occasional) before, during, and after exercise. The goal is to find reliable biomarkers that can quickly and accurately identify a concussion, which is often hard to detect with standard brain scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Saliva biomarker analysis (nucleic acids and proteins)

What this could lead to

If successful, this could lead to a simple, non-invasive saliva test to quickly diagnose concussions in athletes, reducing reliance on subjective assessments.

What could go wrong

This is an early-stage observational study with only 80 participants, so results may not be generalizable. The biomarkers may not prove reliable enough for a diagnostic test.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Brain Concussion traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sys2Diag - Umr9005 Cnrs/Alcen

    RECRUITING

    Montpellier, 34184, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••