First patients test new cancer drug targeting specific tumor marker

NCT ID NCT05735366

Summary

This first-in-human study tested a new drug called SAIL66 in 22 patients with advanced solid tumors that have a specific marker called CLDN6. The main goals were to find a safe dose and see how the body processes the drug, while also checking for any early signs that it might help shrink tumors. This was an early safety study, so determining how well it works against cancer will require larger future trials.

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Contacts and locations

Locations

  • Banner MD Anderson Cancer Center

    Gilbert, Arizona, 85234, United States

  • Cancer Institute Hospital of JFCR

    Tokyo, Koto Ku, 135-8550, Japan

  • Georgia Cancer Center at Augusta University

    Augusta, Georgia, 30912, United States

  • MUSC Hollings Cancer Center

    Charleston, South Carolina, 29425, United States

  • National Cancer Center Hospital

    Tokyo, Chuo Ku, 104-0045, Japan

  • National Cancer Center Hospital East

    Kashiwa, Chiba, 277-8577, Japan

  • Shizuoka Cancer Center

    Shizuoka, Sunto-gun, 411-8777, Japan

  • Tennessee Oncology, PLLC

    Nashville, Tennessee, 37203, United States

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.