New shot shows promise for severe Post-Baby depression

NCT ID NCT02614547

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 31 times

Summary

This study tested an experimental medicine called SAGE-547 in 21 women with severe postpartum depression. The goal was to see if a single injection could quickly reduce depression symptoms compared to a placebo. The trial was small and early-stage, but results could lead to faster relief for new mothers struggling with severe depression.

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Contacts and locations

Locations

  • Sage Investigational Site

    Atlanta, Georgia, 30342, United States

  • Sage Investigational Site

    Worcester, Massachusetts, 01655, United States

  • Sage Investigational Site

    Chapel Hill, North Carolina, 27514, United States

  • Sage Investigational Site

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.