Injectable biostimulators under the microscope: a safety deep dive
NCT ID NCT06993558
First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time
Summary
This trial investigates the safety and tissue effects of two injectable biostimulators—Poly-L-Lactic Acid (PLLA) and Calcium Hydroxyapatite (CaHA)—used for facial rejuvenation in healthy volunteers aged 30 and older. Participants receive one or two treatment sessions, followed by four check-ups to monitor inflammation, deposit formation, and tissue changes using ultrasound. The goal is to better understand how these treatments interact with facial tissues and their safety profile.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Poly-L-Lactic Acid (PLLA) or Calcium Hydroxyapatite (CaHA) injections
- What this could lead to
- If successful, this could confirm the safety of these injectable biostimulators for cosmetic facial rejuvenation.
- What could go wrong
- This is a small, early-phase study in healthy volunteers, so results may not apply to broader populations or reveal rare side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University Hospital Hamburg Eppendorf
RECRUITINGHamburg, Free and Hanseatic City of Hamburg, 20246, Germany
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••